Article: Goal-directed fluid therapy and opioid-sparing technique: Clinical guidance amid doubt and confusion

Kelly Mayson, MD, FRCPC, Ron Collins, MD, FRCPC, Mark F. Masterson, MD, MSc, FRCPC, Jill Osborn, PhD, MD, FRCPC

Optimal management of perioperative fluid therapy remains a highly debated topic. The purpose of optimal fluid management is to maintain or restore effective circulating blood volume during the perioperative period with the goal of maintaining effective blood volume and blood pressure to ensure adequate organ perfusion, while avoiding the risk of either organ hypo- or hyperperfusion … Read more

The full clinical guidance note on opioid-sparing technique is available online (


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